Region Jnkpings ln Odontologiska Institutionen

Use of dental implants in rare disorders

Bergendal B.


Congenital tooth agenesis or acquired early loss of teeth are common clinical features in many rare disorders. Oral rehabilitation with dental implants are strongly indicated in these groups of individuals. The aim was to compile current knowledge on the use of dental implants in individuals with rare disorders, with special emphasis on risks and complications.


A search of PubMed using specific diagnoses as search terms, as well as abstracts from conferences and workshops were used to find reports and publications.


Reports on 170 individuals in 74 publications (October, 2010) and conference abstracts were found, a majority of which were case reports. The results probably reflect an underestimation of reported patients since the search was manual and directed to well-known diagnoses known to be associated with missing teeth.
More than half of the publications referred to treatment in ectodermal dysplasia, which was the diagnosis in more than 70% of reported patients. In many diagnoses oral rehabilitation with dental implants had worked well. However, osseointegration seem to be compromised in hypohidrotic ectodermal dysplasia and in x-linked hypophosphataemic rickets. In osteogenesis imperfecta longer healing time has been advocated. In some rare disorders the surgical technique needs to be adapted to the status of the oral tissues as in dystrophic epidermolysis bullosa where due respect has to be paid to the frail oral mucosa.


The numbers of publications and reports on treatment with dental implants in rare disorders are still limited. A report bias in that a majority of case reports show favourable outcomes of treatment cannot be excluded. Multi-center co-operation and computerised quality registries could open up possibilities to prospectively monitor outcomes of treatments as well as risks and side-effects.



Uppdaterad: 2013-04-03
Anna Thofelt, Avdelningen för odontologisk radiologi Jönköping, Folktandvården